ALine, Inc. – Accelerated Microfluidic Development




ALine, Inc. is a woman-owned and operated microfluidics engineering, rapid prototyping, and low to mid-volume OEM manufacturing firm that was established in 2003. The company was started in the founder’s garage, and has moved twice into facilities that now supports volume manufacture.

The company was founded to address the need for high quality, reproducible microfluidic prototyping to shorten the design build test cycle. We have developed a well characterized rapid prototyping, batch fabrication process to support our client’s development efforts. Our design strategies ensure device fabrication variability does not contribute to assay performance variability.

Rapid means a less than five day turnaround time from receipt of your PO, even for complex builds. Our processes are very well characterized and we can readily accommodate design modifications.

Our focus is on addressing our client’s key design and engineering issues to ensure development timelines are met. We ensure our design and device fabrication processes are scalable for volume production. We are clever, dedicated, and experienced problem solvers with 50+ years of experience in microfluidics.

We work in partnership with your team to help you win in the market.


In 2012, ALine was a finalist for the 2012 Innovation Award sponsored by Patrick Soon Shiong and the LA Business Journal. In 2009, the company was honored as a supplier/partner to the 2009 Medical Design Excellence Award gold winner in the in vitro diagnostics category.

ALine has supported clients whose products have won the Prism Award and the R&D 100 award.

ALine’s customers include, government, industry (NASA, Bio-Rad, Abbott, plus others), universities (Dublin City University, Stanford, UCLA, CalTech, Berkley), research institutes (RTI, CFDRC), and a number of small companies.


Production Equipment:

ALine’s facilities include a class 10K cleanroom, gantry CO2 laser cutting systems, an injection molding press, a 30 ton thermal press, lamination automation, robotic pick and place assembly, UV dispense and cure automation.

Ancillary equipment includes an ultrapure water system, plasma surface treatment capabilities, abrasive cleaning.


Includes a video optical comparator and other microscopy equipment, and an in-house instrument platform for fluidic card testing with an interface to LabView.

Contact angle measurements, and peel strength tests can also be performed.

Quality System

ISO 9001:2008 certified, FDA 21 CFR Part 820 compliant, ISO13485 compliant.