Whole Blood Point-of-Care Test systems must be precise as the results gathered could negatively affect patient diagnoses and treatment. For our clients, we need to design and manufacture a device that can successfully achieve the desired test results using a 2 uL -10 uL sample of whole blood.
There are several challenges that the ALine Team needs to overcome to meet this goal. The first is to ensure that the once the blood sample enters the system, it must be thoroughly mixed with diluent. This mixing has to be done without active pumping as the additional movement could damage the sample. Secondly, the sensor used in the device is wire bonded and mounted on a circuit board, creating an irregular surface around the perimeter of the sensing surface. If not addressed the irregularity could negatively affect the sample process and the results.